Arene ruthenium dithiolato–carborane complexes for boron neutron capture therapy (BNCT)
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منابع مشابه
شبیه سازی چشمه 7li(p,n)7be جهت استفاده در bnct (boron neutron capture therapy)
با توجه به اینکه امروزه بیماران بسیاری در سراسر جهان از سرطان رنج میبرند،دانشمندان در تلاشند روشهای درمانی جدیدتر و بهتری را کشف کنند .یکی از این روشها "درمان بوسیله گیراندازی نوترون توسط بور (bnct)" نام دارد که میتواند یکی از بهترین روشهای مفید و موثر و جایگزین در درمان سرطانهایی از نوع glioblastoma و melanoma نسبت به روشهای متداولی چون شیمی درمانی یا رادیوتراپی باشد.در این روش هدف انجام واکنش...
Investigation the potential of Boron neutron capture therapy (BNCT) to treat the lung cancer
Introduction: Boron neutron capture therapy (BNCT) is recommended to treat the glioblastoma tumor. It is well known that neuron beams are more effective treatment than photon beams to treat hypoxia tumors due to interaction of neutron with nucleus and production of heavy particles such as 7Li and alpha particle. In this study to evaluate the suitability of BNCT for treating of ...
متن کاملBoron Neutron Capture Therapy (BNCT) - Low-Energy Neutron Spectrometer for Neutron Field Characterization -∗)
Boron Neutron Capture Therapy (BNCT) is known to be a promising and new cancer therapy which can kill tumor cells suppressing damage to normal tissues. Recently, accelerator based neutron sources (ABNS) for BNCT are under development especially in Japan. For characterization of the neutron field, we carried out the series study concerning thermal/epi-thermal neutron spectrometry especially for ...
متن کاملBoron Neutron Capture Therapy
A project aimed at the development of an accelerator facility devoted to Boron Neutron Capture Therapy (BNCT) is ongoing at the National Atomic Energy Commission of Argentina [1]. In a first stage of development, the accelerator will be capable of delivering proton or deuteron beams of 30 mA at about 1.4 MeV which is suitable for neutron production through the 9Be(d,n) reaction. In this context...
متن کاملCarborane-Appended Saccharides: Prime Candidates for Boron Neutron Capture Therapy (BNCT) Clinical Trials
Carborane-appended 5-thio-Dglucopyranose (TDG) and deoxyribose derivatives were synthesized and evaluated for accumulation in cancer cells, cytotoxicity, and efficacy in an in vitro boron neutron capture therapy (BNCT) assay. The nidocarborane-appended sugar conjugates were found to be less cytotoxic than their closo-carborane analogues. Biological evaluation with human hepatocellular carcinoma...
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ژورنال
عنوان ژورنال: Journal of Organometallic Chemistry
سال: 2015
ISSN: 0022-328X
DOI: 10.1016/j.jorganchem.2015.05.011